Anti-inflammatory activity of Sebastiania chamaelea (L.) Mull.Arg – An experimental study

Abstract

Inflammation is the immune response raised by the body against an irri-tant. Severity of the inflammation decides the reaction pronounced by the body. Even the impaired diet can cause inflammatory changes in a human body. Anti-inflammatory drugs are capable of reversing the situation. In the current scenario herb based medicinal preparations are really im-portant for meeting the health care needs. Ayurveda have an inevitable role to play in this scenario And presently there is a need to validate the local flora to meet the rising need for herb based medicinal preparations. As an initial step for the purpose the drug Sebastiania chamaelea (L.) Mull.Arg was subjected experimental evaluation of anti-inflammatory ac-tivity. The activity using Formalin- induced paw oedema method were done in Wistar albino rats at three different doses. The data were subject-ed to statistical analysis using one way ANOVA with Tukey’s post hoc test. Statistically significant results were obtained for all test groups when com-pared to the control group .