The effect of Bhavitha Sigru patra choorna (Triturated powder of leaves of Moringa oleifera Lam.) in Hypertension with Hyperlipidemia – A case report

Authors

  • Ankush Zope Final year PG scholar, Department of Dravyagunavijnanam, Government Ayurveda College, Tripunithura, Ernakulam, Kerala.
  • Ansary P Y Professor and HOD, Department of Dravyagunavijnanam, Government Ayurveda College, Tripunithura, Ernakulam, Kerala.

DOI:

https://doi.org/10.55718/kja.283

Keywords:

Bhavitha Sigru patra choorna, Hypertension, Hyperlipidemia, Lipid profile, Blood pressure, Case report

Abstract

Background: Hypertension is the number one health-related risk factor in India and Hyperlipidemia serves as one of its main causes. Both contribute to an estimated 1.6 million deaths annually in India by increasing the risk of ischemic heart disease and stroke. They are the most common non-communicable diseases and major modifiable risk factors for cardiovascular diseases serving as silent killersAwareness and easily assessable treatments of these diseases are very low in India.

Case presentation: A 48-year-old man presented with asymptomatic and newly diagnosed hypertension. Initial evaluation through haematological, serological tests and systemic examination demonstrated hyperlipidemia as a secondary cause in this case. Collected data suggested the absence of any cardiovascular, renal, liver, endocrinal, and neurological disorders. Bhavitha Sigru patra choorna capsule (each of 500mg) was given as an intervention at a dose of 2 capsules twice daily (2gm/day) for 12 weeks. Assessment of systolic and diastolic blood pressure was done before treatment, after 1st week, 2nd week, 3rd week, 4th week, 8th week, and after 12th week. Assessment for lipid profile was done before treatment, after 4th week, 8th week, and 12th week.

Conclusion: The case highlights the effect of the easily available, assessable, cost-effective and shaka varga drug Sigru Patra as a single drug therapy for the management of two associated clinical conditions, hypertension with hyperlipidemia. The study drug Bhavitha Sigru patra choorna was significantly effective in reducing blood pressure and lipid profile parameters of hypertensive patient with hyperlipidemia.

References

World health organisation. https://www.who.int/news-room/fact-sheets/detail/hypertension.

Walker B R, et.al. Davidson’s principles and practice of medicine. Churchill livingstone, Elsevier. 22nd edition (2014); p.607.

Munjal Y P, et.al. API Textbook of medicine. Jaypee brothers medical publishers pvt ltd. New delhi. 10th edition (2015); Vol 1. Chapter 19, p.917.

Warrell D A, et.al. Oxford textbook of medicine. Oxford university press. 5th edition. Volume 2. Chapter 16, p.3023-3037.

Mohan H. Textbook of Pathology. The health sciences publishers, New delhi. 7th edition Reprint (2017); p.676.

Krishna das K V. Textbook of medicine. Jaypee brothers medical publishers pvt ltd, New delhi. 5th edition Reprint (2014); Chapter 123, p.829.

Sembulingam K, et.al. Essentials of Medical physiology. Jaypee brothers medical publishers pvt. Ltd. New delhi. 6th edition (2012); Chapter 103, p.613-616.

Nayak R, et.al. Exam preparatory manual for undergraduates Pathology. Jaypee brothers medical publishers, New delhi. 4th edition (2020); Chapter 16, p.436.

Ministry of Health and family welfare, Government of India. Standard treatment guidelines of hypertension screening, diagnosis, assessment, and management of primary hypertension in adults in India. Feb (2016); p.2.

National nutrition monitoring bureau. Diet and nutritional status of urban population in India and prevalence of obesity, hypertension, diabetes, and hyperlipidemia in urban men and women, (2017). National institute of nutrition. Indian council of medical research, Hyderabad. p.17-24.

The Ayurvedic pharmacopoeia of India, Ministry of Health and family welfare, Department of AYUSH. Government of India. Part 1, Volume 2, S.no. 69, Sigru (leaf), p.155.

Sarangadhara. Sarangadhara samhita, English translation by G prabhakar rao. Chaukhambha publications, New delhi, 1st edition (2013); Madhyama khanda, chapter 6, sloka 1, p.114.

Lochan K. Bhaishajya ratnavali of Govinda dasji bhishagratna, English translation, Chaukhambha Sanskrit samsthan, Varanasi. (2005); Volume 1, Chapter 4, p.89.

Agnivesa. Charaka samhita, Hindi translation by Pandey k et.al. Chaukhambha bharti academy, Varanasi. Revised edition (2019); Part 1, Vimana sthana, chapter 5, sloka 3, p.633.

Sembulingum K, et.al. Essentials of medical physiology. Jaypee brothers medical publishers pvt. Ltd. New delhi. 6th edition (2012); chapter 40, p.249-255.

Sembulingum K, et.al. Essentials of medical physiology. Jaypee brothers medical publishers pvt. Ltd. New delhi. 6th edition (2012); chapter 48, p.301-303.

Agnivesa. Charaka samhita, Hindi translation by Pandey k et.al. Chaukhambha bharti academy, Varanasi. Revised edition (2019); Part 1, Sutra sthana, chapter 26, sloka 42/4, p.440-441.

Sushruta. Sushruta samhita, Hindi commentary by Shastri A. Chaukhambha Sanskrit sansthan, Varanasi. Reprint edition (2012); Part 1, Sutra sthana, chapter 42, sloka 15, p.202-204.

Agnivesa. Charaka samhita, Hindi translation by Pandey k et.al. Chaukhambha bharti academy, Varanasi. Revised edition (2019); Part 1, Sutra sthana, chapter 26, sloka 42/5, p.441.

Sushruta. Sushruta samhita, Hindi commentary by Shastri A. Chaukhambha Sanskrit sansthan, Varanasi. Reprint edition (2012); Part 1, Sutra sthana, chapter 42, sloka 16, p.204.

Agnivesa. Charaka samhita, Hindi translation by Pandey k et.al. Chaukhambha bharti academy, Varanasi. Revised edition (2019); Part 1, Sutra sthana, chapter 26, sloka 42/1, p.438-439.

Sushruta. Sushruta samhita, Hindi commentary by Shastri A. Chaukhambha Sanskrit sansthan, Varanasi. Reprint edition (2012); Part 1, Sutra sthana, chapter 42, sloka 12, p.203.

Bhavamisra. Bhavaprakasa samhita, English translation by Sitaram B. Chaukhambha orientalia, Varanasi. Reprint edition (2013); Prathama khanda, chapter 6, sloka 202, p.279

Sushruta. Sushruta samhita, Hindi commentary by Shastri A. Chaukhambha Sanskrit sansthan, Varanasi. Reprint edition (2012); Part 1, Sutra sthana, chapter 46, sloka 526, p.289.

Vagbhatta. Astanga hridaya, English translation by Shrikantha murthy K R. Chowkhambha krishnadas academy, Varanasi. 10th edition (2014); Part 1, Sutra sthana, chapter 1, sloka 18, p.8.

Bhavamisra. Bhavaprakasa samhita, English translation by Sitaram B. Chaukhambha orientalia, Varanasi. Reprint edition (2013); Prathama khanda, chapter 6, sloka 203, p.279

Bhavamisra. Bhavaprakasa samhita, English translation by Sitaram B. Chaukhambha orientalia, Varanasi. Reprint edition (2013); Prathama khanda, chapter 6, sloka 204, p.280

Vagbhatta. Astanga hridaya, English translation by Shrikantha murthy K R. Chowkhambha krishnadas academy, Varanasi. 10th edition (2014); Part 1, Sutra sthana, chapter 9, sloka 18-19, p.140.

Sushruta. Sushruta samhita, Hindi commentary by Shastri A. Chaukhambha Sanskrit sansthan, Varanasi. Reprint edition (2012); Part 1, Sutra sthana, chapter 40, sloka 13, p.196.

Odii E C, et.al. Antihypertensive effect of Moringa oleifera methanolic extract on cricetomys gambianus. Trop J Nat Prod Res. October (2022); 6(10): p.1695-1700.

Aekthammarat D, et.al. Moringa oleifera leaf extract induces vasorelaxation via endothelium dependent hyperpolarization and calcium channel blockade in mesenteric arterial beds. Clinical and Experimental Hypertension. (2020); 42(6), p.490-501.

Aktar S, et.al. Moringa oleifera methanolic extract inhibits angiotensin converting enzyme activity in vitro which ameliorates hypertension. J adv Biotechnol Exp Ther. (2019); 2(2): p.73-77.

Reddy V, et.al. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG Co-A) reductase in liver microsomes by Moringa oleifera L. polyphenols. IJPSR (2012); Vol. 3(7): p.2510-2516.

Yang Y, et.al. The hypoglycemic and hypolipemic potentials of Moringa oleifera leaf polysaccharide flavonoid complex. International Journal of Biological Macromolecules. June (2022); Vol.210. p.518-529.

Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents. Food chemistry. Dec (2020); Vol.333. p.127478.

Sultana S. Nutritional and functional properties of Moringa oleifera. Metabolism open (2020); Vol.8. p.100061.

Downloads

Published

26-06-2024

How to Cite

Zope, A., & P Y, A. (2024). The effect of Bhavitha Sigru patra choorna (Triturated powder of leaves of Moringa oleifera Lam.) in Hypertension with Hyperlipidemia – A case report. Kerala Journal of Ayurveda, 3(2). https://doi.org/10.55718/kja.283

Issue

Section

Case Reports